Quantitative susceptibility mapping in ischemic stroke patients after successful recanalization

Abstract Quantitative susceptibility mapping (QSM) is a novel processing method for gradient-echo magnetic resonance imaging (MRI). Higher in cortical veins have been observed on maps the ischemic hemisphere of stroke patients, indicating an increased oxygen extraction fraction (OEF). Our goal was to investigate patients after successful recanalization order analyze value QSM predicting tissue prognosis and clinical outcome. We analyzed MR images 23 with due unilateral middle cerebral artery (MCA)-M1/M2 occlusion acquired 24–72 h thrombectomy. The susceptibilities were obtained from compared between territory, ipsilateral non-ischemic MCA territory contralateral territory. As outcome variables, early infarct size functional disability (modified Rankin Scale, mRS) 3–5 months used. median core 41% lower 38% than Strikingly, none prominent vessels high signal found recanalization. Venous values within did not correlate volume or months. Low venous occluded vessel likely indicates poor arising damage. identify peri-infarct as potential surrogate former penumbral areas. no correlation parameters